Hippocampus & Plasticity

​

Outline

1. Hippocampus Anatomy & Circuits

2. Connections are plastic

   • Long-Term Plasticity

   • Short-Term Plasticity

   • Spike Timing-Dependent Plasticity

3. Hippocampus & Spatial Navigation

​

Slides

• Hippocampus & Plasticity

​

Reading For Class

• Kand el: Chapters 67

​

Extra Reading

• Costa et al., 2017: Functional consequences of pre- and postsynaptic expression of synaptic plasticity

​

• Feldman, 2012: The Spike-Timing Dependence of Plasticity

​

• Lisman, 2017: Criteria for identifying the molecular basis of the engram (CaMKII, PKMzeta)

​

• ​vanStrien et al., 2009: The anatomy of memory: an interactive overview of the parahippocampal-hippocampal network

​

• Muller & Remy, 2017: Septo-hippocampal interaction

​

• Fuhrmann et al., 2015: Locomotion, Theta Oscillations, and the Speed-Correlated Firing of Hippocampal Neurons Are Controlled by a Medial Septal Glutamatergic Circuit

​

• Dragoi & Buzsaki, 2007: Temporal Encoding of Place Sequences by Hippocampal Cell Assemblies

​

• Amaral et al., 2007: The dentate gyrus: fundamental neuroanatomical organization (dentate gyrus for dummies)

​

• Yassa & Stark, 2011: Pattern separation in the hippocampus

​

• Yu et al., 2017: Distinct hippocampal-cortical memory representations for experiences associated with movement versus immobility

​

• Sun et al., 2020: Hippocampal neurons represent events as transferable units of experience​

​

• Girardeau et al., 2009: Selective suppression of hippocampal ripples impairs spatial memory