The Cortex

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Outline

1. General Organization of Cortical Circuits

   • Lessons from Henry Markram

2. Motor Cortex

   • The Organization & Planning of Movement

     • ​Internal Error Signals

     • Feedback

   • The Primary Motor Cortex

     • Population Coding

     • Motor Maps

     • The Pre-Motor Cortex

     • Motor Planning

3. Visual Cortex

   • Visual Perception is a Constructive Process

     • Processing Visual Form, Color and Depth

     • Building Receptive Fields

   • Visual Circuits

   • Columnar Organization

   • Circuits Transform Neural Information

   • Perceptrons: A Computational Perspective

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Slides

• The Cortex

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Reading For Class

• Kandel Chapter 37

• Kandel Chapter 38

• Kandel Chapter 25

• Kandel Appendix E (Perceptrons)

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Extra Reading

• Microcircuits Chapter 3: Microcircuitry of the Neocortex (Markram)

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• Markram et al., 2015: Reconstruction and Simulation of Neocortical Microcircuitry

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• Markram et al., 2007: The Intense World Syndrome - an alternative hypothesis for autism

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• Microcircuits Chapter 5: The Motor Control Circuit (Georgopoulus & Stefanis)

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• Hand Knob Area of Premotor Cortex Represents the Whole Body in a Compositional Way (Willett et al., 2020)

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• Michaiel et al., 2019: A Hallucinogenic Serotonin-2A Receptor AgonistReduces Visual Response Gain and Alters TemporalDynamics in Mouse V1

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• Watakabe et al., 2008: Enriched Expression of Serotonin 1B and 2A Receptor Genes in Macaque Visual Cortex and their Bidirectional Modulatory Effects on Neuronal Responses

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• Prasad & Dinkin, 2019: Higher Cortical Visual Disorders

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